TW201340960A

TW201340960A - 眼科用組成物套組

眼科用組成物套組 Download PDF

Info

Publication number: TW201340960A
Authority: TW; Taiwan
Prior art keywords: container; ophthalmic; ophthalmic composition; weight; gga
Prior art date: 2012-02-27

Application number

TW102106502A

Other languages

English (en)

Chinese (zh)

Inventor

Takayuki Miyano

Takahiro Kurose

Original Assignee

Rohto Pharma

Priority date

2012-02-27

Filing date

2013-02-25

Publication date

2013-10-16

2013-02-25 Application filed by Rohto Pharma filed Critical Rohto Pharma

2013-10-16 Publication of TW201340960A publication Critical patent/TW201340960A/zh

Links

239000000203 mixture Substances 0.000 title claims abstract description 145
DJAHKBBSJCDSOZ-AJLBTXRUSA-N (5z,9e,13e)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one;(5e,9e,13e)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C/CCC(C)=O.CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CCC(C)=O DJAHKBBSJCDSOZ-AJLBTXRUSA-N 0.000 claims abstract description 42
229950006156 teprenone Drugs 0.000 claims abstract description 40
239000011521 glass Substances 0.000 claims abstract description 20
239000004417 polycarbonate Substances 0.000 claims abstract description 19
229920000515 polycarbonate Polymers 0.000 claims abstract description 18
239000012611 container material Substances 0.000 claims abstract description 16
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229920000178 Acrylic resin Polymers 0.000 claims abstract description 12
239000004925 Acrylic resin Substances 0.000 claims abstract description 12
KKEYFWRCBNTPAC-UHFFFAOYSA-L terephthalate(2-) Chemical compound [O-]C(=O)C1=CC=C(C([O-])=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-L 0.000 claims abstract description 12
-1 polyethylene Polymers 0.000 claims description 85
239000003889 eye drop Substances 0.000 claims description 24
238000000034 method Methods 0.000 claims description 23
239000003963 antioxidant agent Substances 0.000 claims description 18
230000003078 antioxidant effect Effects 0.000 claims description 17
238000001179 sorption measurement Methods 0.000 claims description 17
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AFFLGGQVNFXPEV-UHFFFAOYSA-N n-decene Natural products CCCCCCCCC=C AFFLGGQVNFXPEV-UHFFFAOYSA-N 0.000 claims description 15
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239000005020 polyethylene terephthalate Substances 0.000 claims description 7
HNZUNIKWNYHEJJ-FMIVXFBMSA-N geranyl acetone Chemical compound CC(C)=CCC\C(C)=C\CCC(C)=O HNZUNIKWNYHEJJ-FMIVXFBMSA-N 0.000 claims description 6
HNZUNIKWNYHEJJ-UHFFFAOYSA-N geranyl acetone Natural products CC(C)=CCCC(C)=CCCC(C)=O HNZUNIKWNYHEJJ-UHFFFAOYSA-N 0.000 claims description 6
125000002350 geranyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 6
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XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
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ZVQOOHYFBIDMTQ-UHFFFAOYSA-N [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide Chemical compound N#CN=S(C)(=O)C(C)C1=CC=C(C(F)(F)F)N=C1 ZVQOOHYFBIDMTQ-UHFFFAOYSA-N 0.000 description 4
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239000001257 hydrogen Substances 0.000 description 4
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230000007794 irritation Effects 0.000 description 4
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